The gameplay in Oddworld: Abe's Oddysee is centered around stealth and strategy. Players must guide Abe through the RuptureFarms facility, avoiding detection by guards and other enemies. Abe can perform a variety of actions, including running, jumping, and using his feet to stun enemies. Players can also use Abe's "soul-sucking" ability to possess and control certain objects and enemies, adding a unique twist to the gameplay.